FLAVONOIDS IN SOME AQUEOUS-ETHANOLIC EXTRACTS FROM HERBA HYPERICI AND THEIR ANTIMICROBIAL ACTIVITY

Rilinda Klosi, Klaudia Hysolli

Abstract


In recent years, herbal products containing St. John’s wort extracts are among the most consumed worldwide. This medicinal plant has a long history of medical use even in Albania. Inhabitants in the regions of Korça and Pogradec quite frequently prepare herbal products using dried flowering tops of the plant Hypericum perforatum L. Alco-holic and oily extracts are the most commonly used. Our study aims to evaluate the influence of alcohol percentage on phytochemical compo-nents extraction, especially on flavonoids. The presence of flavonoids and hypericin was demonstrated using thin layer chromatography. The extracts antimicrobial activity was tested against Staphylococcus aure-us, applying the disc diffusion technique on nutrient agar-broth. Using 50μl/per disc of the extracts prepared with 70 and 80% ethanol the observed inhibition zones were similar, having a diameter of 7 mm. The inhibition zone formed with the same quantity of the oily extract was 8 mm.


Keywords


Flavonoids; aqueous-ethanolic extracts; Herba Hyperici

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Copyright (c) 2015 Rilinda Klosi, Klaudia Hysolli

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